PIONIN (INCI: Quaternium-73) is a well-established, yellow crystalline antimicrobial active developed by Nagase Viita, with a long history of safe use in cosmetics in Japan since the 1950s. It is authorized for use in quasi-drug formulations by the Japanese Ministry of Health and Welfare.

PIONIN provides broad-spectrum antimicrobial activity effective against both gram-positive and gram-negative bacteria, including Propionibacterium acnes, making it suitable for anti-acne, anti-dandruff, and deodorant applications. It is thermally stable, maintains efficacy across a wide pH range, and is photostable when protected from light, supporting reliable preservation performance throughout a product's shelf life.

With its proven efficacy at low use concentrations and flexible compatibility with common cosmetic solvents, PIONIN offers formulators a dependable antimicrobial solution for personal care products requiring targeted preservation and skin benefit performance.

MICONIUM BTMS50 Conditioning agent for use in Hair conditioners, Body and Hand Preparations, Hair Dyes and Colors, Bath Soaps & Shampoos.