AA2G (INCI: Ascorbyl Glucoside) is a stabilized Vitamin C derivative — L-Ascorbic Acid 2-Glucoside — produced through enzymatic technology by Nagase. Unlike pure Vitamin C, AA2G is gradually metabolized in the skin into Vitamin C and glucose via naturally occurring alpha-glucosidase, providing a sustained, time-released supply of active Vitamin C.

This ingredient delivers multiple skin benefits including melanin inhibition, age spot lightening, collagen and hyaluronic acid synthesis support, UV damage reduction, and antioxidant protection. Its excellent formulation stability across various pH levels minimizes discoloration and degradation risk during manufacturing and storage compared to other Vitamin C derivatives.

Approved as a quasi-drug active in Japan for pigmentation claims, COSMOS approved, Halal certified, and China IECIC listed, AA2G is a globally trusted brightening and anti-aging ingredient for skin care and sun care product lines.

Insulin-like growth factor 1 (IGF-1) belongs to the family of insulin-like growth factors that are structurally homologous to proinsulin. Mature IGFs are generated by proteolytic processing of inactive precursor proteins, which contains the N- and C-terminal propeptide regions. Mature human IGF-1 consisting of 70 amino acids has 94% identity with mouse IGF-1 and exhibits cross-species activity. IGF-1 binds IGF-IR, IGF-IIR, and the insulin receptor and plays a key role in cell cycle progression, cell proliferation and tumor progression. IGF-1 expression is regulated by growth hormone. R3 IGF-1 is an 83 amino acid analog of IGF-1 comprising the complete human IGF-1 sequence with the substitution of an Arg (R) for the Glu(E) at position three, hence R3, and a 13 amino acid extension peptide at the N terminus. R3 IGF-1 has been produced with the purpose of increasing biological activity. R3 IGF-1 is significantly more potent than human IGF-1 in vitro. Recombinant Human LR3 Insulin-Like Growth Factor-1 is produced by E.coli expression system, and is produced with raw materials of pharmaceutical applicable level. The host protein residue, nucleic acid residue and common pathogens are strictly controlled, and the production and quality management procedures of the product comply with GMP regulations to ensure the traceability of the production process and all raw materials.

Laminins are large molecular weight glycoproteins constituted by the assembly of three disulfide-linked polypeptides, the α, β and γ chains. Laminin regulates various cellular signaling pathways by binding to cell surface receptors, resulting in the production of more functional cells. Laminin can bind to integrins, polysaccharides, and other substances on the surface of cells. Among them, integrin α6β1 is the main cell adhesion receptor of Laminin and is highly expressed in embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs). Therefore, Laminin, as the main component of the basement membrane, can be used as a clear substrate for culturing ESCs and iPSCs without feeder layers. Recombinant Human Laminin521 E8 is expressed by mammalian cells, and is produced with raw materials of pharmaceutical applicable level. The host protein residue, nucleic acid residue and common pathogens are strictly controlled, and the production and quality management procedures of the product comply with GMP regulations to ensure the traceability of the production process and all raw materials.