ACTIEV CICA CALLUS is Plant-derived exosome isolated and purified from the culture medium of Centella asiatica callus cells. The callus culture is induced using a proprietary process based exclusively on three controlled physical stimuli: UV light, mechanical vibration, and low temperature.This is the world’s first Centella asiatica callus culture produced through a combination of physical stimuli without chemical elicitors. UV stimulation enhances callus cell activity, leading to increased exosome secretion. UV-treated callus cells release exosomes with enhanced skin-relevant benefits, reflecting the adaptive stress response of plant cells under controlled UV exposure. The resulting exosomes support key skin functions, including skin regeneration, hydration, and barrier support. They contribute to the activation of skin repair mechanisms, promote collagen synthesis, and help improve skin moisturization.

L-PDRN FIRST™ is a vegan, world’s first Biome-PDRN. Extracted from Lactobacillus rhamnosus derived from Glycine soya, L-PDRN FIRST™ is a sustainable, microbial-derived alternative to salmon-based PDRN (Polydeoxyribonucleotide), produced through controlled microbial fermentation and purification.
L-PDRN FIRST™ uniquely activates two regeneration pathways: the classical FAK–AKT cascade and the additional p38/ERK pathway. It is 2–8× lighter at the molecular level, enabling deeper and faster skin penetration to support superior skin repair and next-level antioxidant defense.

Lactobacillus is effective in forming immunity and antibacterial substances, normalizing the composition of intestinal bacteria, and inhibiting the production of harmful bacteria. It inhibits the herpes virus and regulates immune function by producing antibacterial substances. It produces natural antibiotics in the small intestine to inhibit the growth of more than 20 types of harmful bacteria and enhances immunity. It promotes digestion by producing enzymes that help digestion of fats, proteins, and dairy products. It also produces vitamin B groups and vitamin K in the intestine.

Skin Barrier Enhancer was developed based on the biological mechanism of skin barrier system in the human body, delivering a bio-mimetic barrier-strengthening action similar to the natural recovery pathways of the skin. It helps reinforce weakened barrier structures and reduce irritation.