コスメとトイレタリー

Lowenol AHL-N is minoxidol-like derivative, that promotes vasodilation around the hair follicles. The mechanism is based on activation of potassium ion channels and improvement of microcirculation in the scalp, facilitating nutrient absorption and stimulating the proliferation of hair papilla cells. Additional activity inhibits the activity of 5α-reductase, thereby reducing the conversion of testosterone to dihydrotestosterone (DHT), preventing hair follicle miniaturization. Clinical testing confirms significant hair loss reduction, improvement of local hair count, hair density, and hair diameter.

Lowenol AHL-U (DIAMINOPYRIMIDINE OXIDE) inhibits lysyl hydroxylase enzyme (LH) mRNA expression, interfering with fibroblast collagen production and prevents mature collagen deposition, thereby preventing hair follicle hardening and contraction-induced hair loss. Compared to other hair loss treatments, it does not affect blood pressure, offering enhanced safety. Lowenol AHL-U also inhibits the activity of 5α-reductase, thereby reducing the conversion of testosterone to dihydrotestosterone (DHT), preventing hair follicle miniaturization. Clinical testing confirms significant hair loss reduction, improvement of local hair count, hair density, and hair diameter.

PEACHCALM (HD) for sensitive skin is a scalp-soothing active inspired by the natural healing mechanisms of peach trees. It helps reduce scalp sensitivity by regulating cell proliferation, metabolism, and inflammation associated with microbial imbalance (e.g., C. acnes). Its efficacy is rooted in the protective role of plant gums, which naturally limit the spread of bacterial and fungal pathogens in damaged tissues. By mimicking the gum/resin secreted by peach trees to heal and protect themselves, PEACHCALM reinforces scalp defense. Leveraging advanced High-Pressure Homogenization technology, it achieves improved bioavailability and heightened physiological activity, ensuring optimal performance and ease of use in modern formulations.