Personal Care Ingredients

Real‑MADECA PDRN(HD) is a personal care ingredient developed by Dermalab Co., Ltd., designed to support advanced skin care formulations with a modern, bio-inspired approach. Derived from plant-based sources, this ingredient is positioned for brands seeking innovative alternatives aligned with evolving consumer expectations in skincare.

Real‑MADECA PDRN(HD) is commonly used in skincare concepts where a focus on skin vitality, comfort, and overall skin condition is desired. Its composition is designed to support formulations targeting daily care and specialized skin routines, making it suitable for premium and functional personal care products.

As part of Dermalab’s personal care ingredient portfolio, Real‑MADECA PDRN(HD) reflects the manufacturer’s expertise in developing ingredients intended for professional cosmetic applications. Further technical details, formulation guidance, and supporting documentation are available for registered users exploring this ingredient in greater depth.

MELATREPEIN 5000 are produced in melanocytes and transferred to neighboring keratinocytes, where they are naturally degraded by autophagy. However, constant exposure to sunlight or changes in hormonal levels may force cell organelles and enzymes to lose their functions, resulting in slowdown of melanosome degradation. Accumulation of survived melanosomes in keratinocytes result in skin pigmentation. MelaTrepein^TM5000 is a dual targeting solution to prevent or reduce skin pigmentation by activating autophagic process to break down melanosomes already existing in keratinocytes, and by blocking new melanosome uptake into keratinocytes at the same time.

Olive Active Maslinico is a form of maslinic acid extracted from olive oil. It stimulates cell renewal, rejuvenation and reduces skin degradation due to inflammations, available in powder and liquid (encapsulated) form.

ACTIEV CICA CALLUS is Plant-derived exosome isolated and purified from the culture medium of Centella asiatica callus cells. The callus culture is induced using a proprietary process based exclusively on three controlled physical stimuli: UV light, mechanical vibration, and low temperature.This is the world’s first Centella asiatica callus culture produced through a combination of physical stimuli without chemical elicitors. UV stimulation enhances callus cell activity, leading to increased exosome secretion. UV-treated callus cells release exosomes with enhanced skin-relevant benefits, reflecting the adaptive stress response of plant cells under controlled UV exposure. The resulting exosomes support key skin functions, including skin regeneration, hydration, and barrier support. They contribute to the activation of skin repair mechanisms, promote collagen synthesis, and help improve skin moisturization.