Refarmed Chemicals is proud to present its esteemed pharmaceutical compound, Butamirate Citrate, an integral antitussive agent designed to alleviate discomfort in patients suffering from dry, unproductive coughs. Our Butamirate Citrate is an optimal choice for those grappling with upper respiratory tract infections, bronchitis, pneumonia, and even asthma, providing relief from persistent coughing that often accompanies these conditions. Crafted with meticulous attention to quality, our Butamirate Citrate appears as a white to yellowish powder with a slightly waxy texture, assuring ease of incorporation into various dosage forms. Its chemical identity is confirmed through rigorous testing, including the citrate and IR tests, maintaining a high level of purity and performance. The compound exhibits excellent solubility, being freely soluble in water and ethanol (96%), which ensures flexibility in formulation. Adhering to the gold standard of production, Butamirate Citrate holds GMP certification and is characterized by a precise pH range of 3.5 to 4.0. Our commitment to safety and efficacy is evidenced by the thorough analysis that guarantees an assay value between 98.0% - 102.0%, with minimal impurities. Heavy metals content is strictly controlled to ensure patient safety, and residual solvents such as Isopropanol, MTBE, Isopropyl ether, and Toluene are meticulously regulated. Our Butamirate Citrate operates by targeting the cough center in the medulla oblongata to effectively suppress cough reflexes, without reliance on opioids. This action provides a duration of relief for 4-8 hours, allowing for a more comfortable recovery process for the patient. It is suitable for adults and children over the age of 6, with dosage adjustments available to accommodate individual patient responses and tolerability. In conclusion, Refarmed Chemicals' Butamirate Citrate stands as a testament to our dedication to delivering pharmaceutical ingredients of the highest caliber. Our product not only meets the robust demands of the pharmaceutical industry but also provides a critical component for the formulation of efficacious cough suppressants that cater to a wide range of patients.

Products still subject to third-party patent protection might be available solely for R&D purposes.

Benserazide Hydrochloride, offered under REFARMED CHEMICALS—a subsidiary of the DKSH Group—is an essential pharmaceutical ingredient tailored for the robust demands of the medical industry. Specifically formulated for the management of Parkinson’s disease, Benserazide Hydrochloride serves as a monoamine oxidase B (MAO-B) inhibitor. When synergistically combined with levodopa, it not only amplifies the efficacy of the treatment but also mitigates associated side effects such as nausea, enhancing the quality of life for patients suffering from this neurodegenerative condition. Our Benserazide Hydrochloride emerges as a white to off-white crystalline powder, a testament to its purity and quality. The compound exhibits admirable water solubility, ensuring ease of formulation and bioavailability. Its molecular identity, C10H14N2O3·HCl, with a molecular weight of 234.7 g/mol, aligns with rigorous pharmaceutical prerequisites. Our product delivers through a strict adherence to quality with an assay value ranging from 98.5% to 101.0%, guaranteeing a high-caliber substance with minimal impurity content. REFARMED CHEMICALS prioritizes safety and compliance, validating Benserazide Hydrochloride's authenticity with the IR and Chlorides test among others, and acknowledges the product’s conscientious solubility in water and minimal solubility in anhydrous ethanol. We maintain stringent control on residual solvents, ensuring ethanol levels remain below 5000 ppm and methanol below 3000 ppm. Administered orally, this pharmaceutical agent's dosage is contingent upon individual patient needs and medical recommendations, subject to professional healthcare guidance. Despite its profound benefits, it should be noted that Benserazide Hydrochloride is contraindicated for patients with severe hepatic or renal impairments and requires cautious use in patients with a history of cardiovascular diseases, orthostatic hypotension, or psychiatric conditions. Interaction with opioids and antidepressants necessitates careful management. Upholding the highest standards, our product is compliant with Good Manufacturing Practice (GMP) and holds the Certificate of Suitability (CEP)—a rigorous certification ensuring consistency in high-quality production for our corporate customers. With REFARMED CHEMICALS, you are guaranteed a product that not only addresses the therapeutic needs but also embodies the precision and reliability sought after in the pharmaceutical industry.

Products still subject to third-party patent protection might be available solely for R&D purposes.

**Thonzylamine HCl: Efficacious Antihistamine for Allergic Relief** Thonzylamine HCl, offered under the REFARMED CHEMICALS brand, is a potent first-generation antihistamine tailored for the pharmaceutical industry's demand for reliable and effective allergy symptomatic treatment. This compound, classified under the alkylamine class, serves as a crucial ingredient for medications formulated to alleviate discomfort from common allergic reactions such as hay fever, allergic rhinitis, and hives. As an active pharmaceutical ingredient (API), it plays a significant role in delivering relief to countless individuals affected by these prevalent conditions. Primarily presented as a white to slightly yellowish crystalline powder, Thonzylamine HCl upholds a high standard of purity, with an assay value ranging from 98.5% to 101.0%. Its manufacturing process is governed by stringent EU GMP certifications, ensuring that every batch meets the requirements for quality and consistency—attributes of paramount importance for our corporate clientele. Thonzylamine HCl works by effectively intercepting histamine's action—an organic compound responsible for numerous allergic symptoms. By blocking histamine receptors, this API diminishes the intensity of effects such as sneezing, runny nose, and itchy eyes, dramatically improving quality of life for allergy sufferers. Administered orally, the recommended dosage for adults and children over the age of 12 is between 50-100 mg, three to four times daily, as prescribed by healthcare professionals. Furthermore, precautions are advised in patients with liver or kidney disease, and the substance should be avoided by individuals with sensitivities to its components or conditions like acute asthma, narrow-angle glaucoma, or urinary retention. Additionally, users should be cautious about engaging in activities requiring cognitive sharpness, such as operating machinery or driving, as Thonzylamine HCl has sedative properties that may impair alertness. Our website offers complete details, including the chemical structure (2-[(2-Dimethylaminoethyl)(p-methoxybenzyl)amino]pyridine hydrochloride) and analytical specifications that reveal its physical and chemical properties. Rest assured, partnering with our company provides you with access to an essential product that epitomizes the excellence and dedication to the pharmaceutical supply chain, delivering health and wellness to the community.

Products still subject to third-party patent protection might be available solely for R&D purposes.