Refarmed Chemicals is proud to present its esteemed pharmaceutical compound, Butamirate Citrate, an integral antitussive agent designed to alleviate discomfort in patients suffering from dry, unproductive coughs. Our Butamirate Citrate is an optimal choice for those grappling with upper respiratory tract infections, bronchitis, pneumonia, and even asthma, providing relief from persistent coughing that often accompanies these conditions. Crafted with meticulous attention to quality, our Butamirate Citrate appears as a white to yellowish powder with a slightly waxy texture, assuring ease of incorporation into various dosage forms. Its chemical identity is confirmed through rigorous testing, including the citrate and IR tests, maintaining a high level of purity and performance. The compound exhibits excellent solubility, being freely soluble in water and ethanol (96%), which ensures flexibility in formulation. Adhering to the gold standard of production, Butamirate Citrate holds GMP certification and is characterized by a precise pH range of 3.5 to 4.0. Our commitment to safety and efficacy is evidenced by the thorough analysis that guarantees an assay value between 98.0% - 102.0%, with minimal impurities. Heavy metals content is strictly controlled to ensure patient safety, and residual solvents such as Isopropanol, MTBE, Isopropyl ether, and Toluene are meticulously regulated. Our Butamirate Citrate operates by targeting the cough center in the medulla oblongata to effectively suppress cough reflexes, without reliance on opioids. This action provides a duration of relief for 4-8 hours, allowing for a more comfortable recovery process for the patient. It is suitable for adults and children over the age of 6, with dosage adjustments available to accommodate individual patient responses and tolerability. In conclusion, Refarmed Chemicals' Butamirate Citrate stands as a testament to our dedication to delivering pharmaceutical ingredients of the highest caliber. Our product not only meets the robust demands of the pharmaceutical industry but also provides a critical component for the formulation of efficacious cough suppressants that cater to a wide range of patients.

Products still subject to third-party patent protection might be available solely for R&D purposes.

Benserazide Hydrochloride, offered under REFARMED CHEMICALS—a subsidiary of the DKSH Group—is an essential pharmaceutical ingredient tailored for the robust demands of the medical industry. Specifically formulated for the management of Parkinson’s disease, Benserazide Hydrochloride serves as a monoamine oxidase B (MAO-B) inhibitor. When synergistically combined with levodopa, it not only amplifies the efficacy of the treatment but also mitigates associated side effects such as nausea, enhancing the quality of life for patients suffering from this neurodegenerative condition. Our Benserazide Hydrochloride emerges as a white to off-white crystalline powder, a testament to its purity and quality. The compound exhibits admirable water solubility, ensuring ease of formulation and bioavailability. Its molecular identity, C10H14N2O3·HCl, with a molecular weight of 234.7 g/mol, aligns with rigorous pharmaceutical prerequisites. Our product delivers through a strict adherence to quality with an assay value ranging from 98.5% to 101.0%, guaranteeing a high-caliber substance with minimal impurity content. REFARMED CHEMICALS prioritizes safety and compliance, validating Benserazide Hydrochloride's authenticity with the IR and Chlorides test among others, and acknowledges the product’s conscientious solubility in water and minimal solubility in anhydrous ethanol. We maintain stringent control on residual solvents, ensuring ethanol levels remain below 5000 ppm and methanol below 3000 ppm. Administered orally, this pharmaceutical agent's dosage is contingent upon individual patient needs and medical recommendations, subject to professional healthcare guidance. Despite its profound benefits, it should be noted that Benserazide Hydrochloride is contraindicated for patients with severe hepatic or renal impairments and requires cautious use in patients with a history of cardiovascular diseases, orthostatic hypotension, or psychiatric conditions. Interaction with opioids and antidepressants necessitates careful management. Upholding the highest standards, our product is compliant with Good Manufacturing Practice (GMP) and holds the Certificate of Suitability (CEP)—a rigorous certification ensuring consistency in high-quality production for our corporate customers. With REFARMED CHEMICALS, you are guaranteed a product that not only addresses the therapeutic needs but also embodies the precision and reliability sought after in the pharmaceutical industry.

Products still subject to third-party patent protection might be available solely for R&D purposes.

Procaterol HCl Hemihydrate: A Specialized Compound for Asthma and COPD Management In an industry where efficacy and patient safety are paramount, REFARMED CHEMICALS' Procaterol HCl Hemihydrate emerges as a vital pharmaceutical ingredient. This beta-2 adrenergic receptor agonist plays a crucial role in the medical management of respiratory conditions such as asthma and chronic obstructive pulmonary disease (COPD). By targeting bronchial smooth muscles, it facilitates breathing by promoting bronchodilation and reducing inflammation, a testament to its pharmacological prowess. The chemical composition of Procaterol HCl Hemihydrate, C11H16Cl2N2O·0.5H2O, is synthesized to achieve a precise molecular weight of 265.14 g/mol, ensuring the utmost purity and effectiveness. Appearing as a white to off-white crystalline powder, it maintains its integrity as slightly soluble in both water and organic solvents, indicative of its carefully regulated physical properties. Developed with strict adherence to global standards, this product is backed by comprehensive documentation such as EU DMF and JDMF, and is certified under EU GMP, underscoring REFARMED CHEMICALS' commitment to quality. The substance exhibits a melting point of ≤195°C and a clear aqueous solution at 3.3%, ensuring its stability and consistency in formulation. Safety is paramount; thus, precautions are advised for patients with pre-existing cardiovascular conditions, and careful monitoring is recommended to prevent adverse effects such as tachycardia or tremors. With individualized dosage, delivered usually through inhalation methods like metered-dose inhalers or dry powder inhalers, this pharmaceutical ingredient provides a targeted approach to managing respiratory ailments. REFARMED CHEMICALS is proud to offer a product that meets the rigorous demands of the pharmaceutical industry while improving the quality of life for patients globally. Contraindicated only in those with a known hypersensitivity to beta-2 adrenergic agonists or a recent myocardial infarction, Procaterol HCl Hemihydrate is a testament to the company's mission—delivering growth in the pursuit of health care advancements.

Products still subject to third-party patent protection might be available solely for R&D purposes.

REFARMED CHEMICALS presents RamoseTron HCl, a high-purity pharmaceutical agent that serves as a critical component in mitigating the discomforting side effects associated with cancer treatments. Primarily utilized for its antiemetic properties, RamoseTron HCl is an effective serotonin (5-HT3) receptor antagonist, specifically formulated to prevent and treat nausea and vomiting induced by chemotherapy and radiation therapy. This product showcases our commitment to improving patient care during the rigorous journey of cancer treatment. RamoseTron HCl exhibits a remarkable ability to bind and block 5-HT3 receptors both in the gastrointestinal tract and the central nervous system—areas pivotal in cueing nausea and vomiting. By interrupting the signal transmission that triggers these adverse reactions, RamoseTron HCl lessens the severity and frequency of these symptoms, providing patients with much-needed relief. Tailored for adults and adolescents, RamoseTron HCl is administered orally or intravenously, dosed accordingly to align with the intensity of the emetogenic chemotherapy protocols. It ensures a rapid absorption with an extensive distribution throughout the body, assuring efficacy. The product is presented as a white to slightly yellowish-white crystalline powder, notable for its solubility in methanol, water, and ethanol—making it versatile for various pharmaceutical formulations. It meets rigorous quality standards, with certifications such as EU GMP, affirming its adherence to the highest production protocols. While offering substantial aid to cancer patients, healthcare providers must be attentive to possible contraindications and exercise caution in patients with specific medical conditions. Adverse effects, while generally manageable, must also be considered in the comprehensive patient care plan. REFARMED CHEMICALS' RamoseTron HCl is more than a medicine; it is a supportive ally for patients and healthcare providers in the fight against cancer and its challenging treatment side effects. Our product’s detailed specifications, as seen in the provided image, underscore our commitment to transparency and quality assurance.

Products still subject to third-party patent protection might be available solely for R&D purposes.