MELATREPEIN 5000 are produced in melanocytes and transferred to neighboring keratinocytes, where they are naturally degraded by autophagy. However, constant exposure to sunlight or changes in hormonal levels may force cell organelles and enzymes to lose their functions, resulting in slowdown of melanosome degradation. Accumulation of survived melanosomes in keratinocytes result in skin pigmentation. MelaTrepein^TM5000 is a dual targeting solution to prevent or reduce skin pigmentation by activating autophagic process to break down melanosomes already existing in keratinocytes, and by blocking new melanosome uptake into keratinocytes at the same time.

TUMERIC EXTRACT (HD) Curcuma Longa, commonly known as turmeric, has many benefits. Topical applications of personal care products containing turmeric extract can significantly improve facial skin elasticity and decreased the number of gelatinase-positive stratum corneum clusters in human facial skins. Turmeric is an effective ingredient to improve skin condition and to prevent skin from photoaging by suppressing activation of gelatinase chronically caused by UV..

Cosphaderm® Panthenol natural is the natural version of the well-established active ingredient D-Panthenol. Renowned for its versatile benefits, Panthenol is an indispensable addition to a wide range of formulations. This ingredient supports the skin’s natural barrier, helping to protect against external stressors while promoting hydration. Its calming and anti-inflammatory properties make it an excellent choice for addressing irritation, while its wound-care capabilities aid in skin recovery and repair. Its ability to strengthen skin, hair and nails make it an ideal all-rounder active for every formulation. Sourced sustainably, our Cosphaderm Panthenol natural delivers exceptional quality, aligning with growing demand for effective and eco-friendly cosmetic ingredients.