Cosmetics & Toiletries Ingredients

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CELYSCENCE™

Glycerin (and) Water (and) Silybum Marianum Extract

CELYSCENCE™ mitigates the impacts of senescence. It selectively eliminates senescent cells, preventing them from irreversibly inducing damage, and down-regulates their secretion of molecules that cause additional harm. Celyscence™ can even reprogram senescent cells and reverse their loss of functionality. Use Level: 1-5%.

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MELATREPEIN 5000

0.5% MelaTrepeinTM; 2% 1,2-Hexanediol; 97.5% Water

MELATREPEIN 5000 are produced in melanocytes and transferred to neighboring keratinocytes, where they are naturally degraded by autophagy. However, constant exposure to sunlight or changes in hormonal levels may force cell organelles and enzymes to lose their functions, resulting in slowdown of melanosome degradation. Accumulation of survived melanosomes in keratinocytes result in skin pigmentation. MelaTrepein^TM5000 is a dual targeting solution to prevent or reduce skin pigmentation by activating autophagic process to break down melanosomes already existing in keratinocytes, and by blocking new melanosome uptake into keratinocytes at the same time.

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Ingredients that foster sustainable development by aiding in climate change mitigation or adaptation, promoting water conservation, supporting a circular economy, preventing pollution, safeguarding biodiversity, or advancing a more ethical and socially just economy.

ReCol®17 (Sponge)

Sr-(Decapeptide-63 sh-Polypeptide-148 Hexapeptide-40)

ReCol^®17 (Sponge), TTB1-02-S also known as transmembrane collagen, is rarely found in the skin, mucous membranes, and eyes. Serving as a double-sided adhesive, it connects cells to the extracellular matrix, while nourishing stem cell renewal. ReCol^®17 (Sponge) represents a breakthrough solution for optimal cell migration—a pivotal factor not only in combating skin aging but also in nurturing hair follicles. Our patented amino acid sequence in ReCol^®17 (Sponge) boasts the highest number of active sites, ensuring unparalleled efficacy.

• In skincare, ReCol^®17 (Sponge) reinforces resilience against reactive oxygen species (ROS), effectively delaying UV-induced skin aging. Moreover, the increased presence of Collagen Type XVII significantly contributes to wrinkle reduction.

• In haircare, clinical studies validate the remarkable benefits of ReCol^®17 (Sponge). Not only does it prevent hair loss, but it also enhances hair density and diameter, paving the way for voluminous, healthier-looking hair without any hormones-related side effects.

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UNIGEN, INC.

BAKUTROL®

Hydrolyzed Psoralea Corylifolia Seeds

Bakutrol® is a proprietary cosmetic active clinically proven to visibly reduce acne blemishes, particularly those associated with inflammatory acne. It is a broad-spectrum antimicrobial and anti-inflammatory agent that also acts as an anti-acne solution. Bakutrol® effectively targets both the bacterial and inflammatory components of problematic skin conditions. Its key ingredient, bakuchiol (not less than 60%), has been shown to inhibit acne-causing bacteria and block COX/LOX inflammatory pathways. Natural, safe, and well-tolerated, Bakutrol® has no adverse effects and can be easily formulated with other ingredients, making it ideal for use in anti-acne and topical skincare products.

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