Pharmaceutical Ingredients Catalog | APIs & Excipients

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HEPES FREE ACID, GMP, EXCIPIENT GRADE

HEPES FREE ACID, GMP, EXCIPIENT GRADE is a zwitterionic buffer used to maintain pH of media used in cell cultures. It is one of Good’s twelve buffers that has a pKa value similar to its pH value making it an ideal buffer for pH maintenance. It has only one restriction, it interferes with the Folin protein assay. This buffer can form radicals so it is not suitable for redox studies. HEPES is used as a Good’s buffer because it has low UV absorptivity, minimal reactivity,stable pH and is soluble in water.

Pharmazeutische Inhaltsstoffe

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Inhaltsstoffe, die eine nachhaltige Entwicklung fördern, indem sie zur Abschwächung oder Anpassung an den Klimawandel beitragen, den Wasserschutz fördern, eine Kreislaufwirtschaft unterstützen, Umweltverschmutzung verhindern, die Biodiversität schützen oder eine ethischere und sozial gerechtere Wirtschaft vorantreiben.

SODIUM DECANOATE

Sodium Decanoate, or sodium caprate, is the sodium salt of caproic acid, a 10-carbon saturated fatty acid. It has amphiphilic character and can form micelles and liquid crystalline phases in aqueous solution. Sodium decanoate’s properties may help elucidate the transport of biologically active molecules and as a final component of a finished drug product, it may serve to enhance the bioavailability of the API. BioSpectra’s Bio Excipient Grade of Sodium Decanoate is supported by a Type IV drug master file submitted with the FDA.

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SODIUM HYDROXIDE SOLUTION 10N (30%), GMP GRADE MADE IN THE USA LOW CHLORIDE NAHY-4150

High Purity Sodium Hydroxide 10N is intended for use in critical pharmaceutical processes both upstream and downstream. This product is manufactured utilizing a proprietary, fully dedicated, validated GMP system that utilizes multiple manufacturing and purification steps to achieve high purity results without the use of pellets.

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GUANIDINE THIOCYANATE, GMP EXCIPIENT GRADE GTHI-3220

Guanidine Thiocyanate is a chaotropic agent. As one of the strongest protein denaturants, it inactivates nucleases more than twice as fast as Guanidine Hydrochloride. Guanidine Thiocyanate is preferred for the purification of RNA because it dissociates the RNA into its nucleic acids and protein forms. Higher molarity solutions of Guanidine Thiocyanate irreversibly inactivate RNase. Guanidine Thiocyanate causes proteins to dissolve readily, thus disintegrating cellular structures.

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