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From Liquids to free flowing Powders: How Syloid® XDP 3150 Simplifies Formulation Challenges

In the pharmaceutical and nutraceutical industries, one of the biggest challenges formulators face is working with oily actives, sticky herbal extracts, and lipid-based delivery systems. These ingredients often create processing difficulties, impacting stability, bioavailability, and overall manufacturing efficiency.
 
As the trusted distributor of Grace’s Syloid® XDP 3150 in Australia and New Zealand, DKSH provides innovative solutions to help manufacturers overcome these challenges and achieve high-quality free-flowing powders, making them easier to process, encapsulate, or compress into tablets.

What is Syloid® XDP 3150?

Syloid® XDP 3150 is a high-performance silica excipient developed by Grace, a global leader in specialty chemicals and materials. It is specifically engineered to enhance oral dosage design by transforming challenging liquid ingredients into free-flowing, stable powders.
 
This unique functionality makes it an ideal excipient for pharmaceutical, nutraceutical, and dietary supplement formulations- making it a versatile ingredient.

Key Benefits of Syloid® XDP 3150

  • Transforms liquids into powders: Converts oily actives, lipid-based formulations, and sticky extracts into dry, flowable powder.
  • Supports multiple dosage formats: Suitable for tablets, hard gelatine capsules, sachets.
  • Enhances API release: Facilitates more efficient and consistent release of active pharmaceutical ingredients for improved bioavailability.
  • Enables solvent-free oil absorption: Oils penetrate the porous structure of Syloid® XDP silica without the need for solvents, surfactants, or drying steps.
  • Optimises manufacturing processes: Improves powder flow, tablet hardness, and reduces friability, leading to greater efficiency.
  • Globally compliant: Meets pharmacopeia standards including USNF, EP, JP, and FCC.

Applications in Pharmaceutical & Nutraceutical Formulations

Syloid® XDP is especially valuable for:
  • Herbal extracts and probiotics: Stabilises sticky, wet materials for easy incorporation into solid dosage forms without compromising potency or stability.
  • Oily actives and lipid-based systems: Ideal for lipidic and oily formulations, it transforms liquids into free-flowing solids that maintain consistent dosage accuracy and improve formulation reproducibility.
  • Nutraceutical powders and dietary supplements: Improves stability, handling, and shelf-life, helping brands deliver more reliable, high-quality supplements.

Why Choose DKSH as Your Distribution Partner

As the authorized distributor of Grace’s Syloid® XDP 3150 in Australia and New Zealand, DKSH combines:
  • Deep market expertise in pharmaceutical and nutraceutical sectors.
  • Comprehensive formulation support from technical specialists.
  • Supply chain reliability ensuring consistent product availability.
Through DKSH, manufacturers can confidently access Grace’s innovative excipient technology and optimize product development from concept to market launch.

How Syloid® XDP 3150 Works

  • Adsorption: Liquid or semi-solid actives are adsorbed onto the porous silica structure.
  • Transformation: The liquid is encapsulated within the silica matrix, forming a stable, solid intermediate.
  • Integration: The resulting free-flowing powder can be easily mixed, compressed, or encapsulated.
This process enhances not only stability and uniformity but also bioavailability, resulting in superior product performance.
 
FAQs About Syloid® XDP 3150
1. What is Syloid® XDP 3150 used for?
: Syloid® XDP 3150 is used to convert oily actives, lipid-based systems, and sticky herbal extracts into free-flowing solid powders for stable dosage forms.
2. How does Syloid® XDP 3150 improve formulation stability?
: It enhances powder flow, tablet hardness, and uniform distribution of active ingredients, resulting in improved stability and consistency.
3. Is Syloid® XDP 3150 pharmacopeia compliant?
: Yes, it meets major pharmacopeia standards, including USNF, EP, JP, and FCC, ensuring global regulatory compliance.
4. Who distributes Syloid® XDP 3150 in Australia and New Zealand?
: DKSH is the authorized distributor of Grace’s Syloid® XDP 3150 in Australia and New Zealand.
5. Can Syloid® XDP 3150 be used in nutraceutical formulations?
: Absolutely. It is ideal for nutraceuticals, helping stabilize and solidify liquid or semi-solid ingredients into consistent, easy-to-formulate powders.
 
Conclusion
With Grace’s Syloid® XDP 3150, manufacturers can confidently tackle formulation challenges of working with liquid and sticky ingredients, improving stability, bioavailability, and process efficiency across a wide range of pharmaceutical and nutraceutical formulations.
 
Through DKSH Discover’s distribution network and formulation expertise, manufacturers gain reliable access to this innovative silica excipient- helping them develop next-generation products that meet both regulatory and consumer expectations.
Contact us here if you want to know more about performance studies!
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