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Unlocking Nature’s Power for Radiant Skin and Hair by Trehalose 100 by Nagase

What is Trehalose 100?

Trehalose 100, created by Nagase Personal Care, is a premium, nature-inspired ingredient that blends the resilience of plants with the precision of science. Known as “Nature’s Protector,” it addresses one of the most essential needs in personal care — moisture preservation and defense against environmental stress.

At the core of Trehalose 100 lies trehalose, a non-reducing disaccharide made up of two glucose molecules linked by an a,a-1,1 glycosidic bond. Naturally found in plants, microorganisms, and most famously in the resurrection plant (Selaginella lepidophylla), trehalose has a unique ability to replace water in plant tissues, protecting cellular structures and enabling revival after complete dehydration.

This natural survival mechanism translates beautifully into skincare and haircare formulations, offering unmatched hydration and protection.

The Science Behind Trehalose 100

Your skin’s stratum corneum — its outermost layer — is just 0.02 mm thick but plays a critical role in maintaining optimal hydration levels of 20–30%. Healthy skin depends on a fine balance of natural moisturizing factors, keratin, intercellular lipids, and sebum.

Trehalose 100 helps maintain this delicate equilibrium by:

  • Locking in moisture to prevent transepidermal water loss (TEWL)

  • Supporting intercellular lipid structures for stronger barrier function

  • Protecting against dryness-induced itching and irritation

Its ability to replicate the resurrection plant’s moisture-preserving mechanism makes Trehalose 100 a game-changer for skin and hair care.

Key Benefits of Trehalose 100 for Skin & Hair

1. Intense Hydration and Moisture Retention

Trehalose 100 deeply hydrates the skin by maintaining its natural water-holding capacity. In low-humidity environments, it outperforms glycerin, ensuring lasting softness and comfort.

2. Strengthens the Skin Barrier

By promoting the formation of lamellar structures in intercellular lipids, Trehalose 100 reinforces the skin’s natural defense layer, keeping it healthy, smooth, and resilient.

3. Soothes Dryness & Reduces Irritation

For individuals with dry, flaky, or sensitive skin, Trehalose 100 helps reduce itching and discomfort by locking in essential moisture.

4. Enhances Hair & Scalp Health

Its hydrating and protective properties make it ideal for haircare formulations like shampoos, conditioners, and leave-in treatments, leaving hair softer, shinier, and easier to manage.

Clinically Proven Performance

Trehalose 100’s benefits are backed by research:

  • A 14-day clinical study on women with dry skin showed that formulas containing 3% Trehalose 100 significantly improved hydration, while placebo formulas showed no visible results.

  • In low-humidity conditions, Trehalose 100 demonstrated superior moisture retention compared to glycerin.

  • It promotes a stronger, healthier skin barrier without compromising formulation stability or texture.

  • Additionally, it helps suppress unpleasant raw material odors, improving the sensorial experience of cosmetic products.

Versatility in Cosmetic Formulations

Trehalose 100’s formulation-friendly properties make it suitable for a wide range of personal care products:

  • Skincare: Lotions, serums, toners, gels, creams

  • Body care: Moisturizers, body lotions, and balms

  • Haircare: Shampoos, conditioners, and hair masks

  • Oral care: Toothpaste and mouthwash

Recommended usage concentrations:

  • 0.1% for oral care formulations

  • Up to 5% for skincare, body care, and haircare products

Its whitish, odorless crystalline powder form is pH-stable, heat-resistant, and easy to incorporate into formulations, ensuring consistent performance.

Why Choose Trehalose 100 by Nagase

In a beauty market where consumers demand products that are effective, responsibly sourced, and environmentally friendly, Trehalose 100 is a standout ingredient. It offers product developers the ability to create high-performance formulations that deliver superior hydration, barrier protection, and skin comfort while meeting modern standards of purity and sustainability. With its proven benefits, natural origin, and strong ethical credentials, Trehalose 100 is set to become a cornerstone in the next generation of skincare and haircare innovations, uniting the strength of nature with the advancements of cosmetic science.

To learn more about Trehalose 100 by Nagase and request samples, register on DKSH Discover and unlock exclusive product details today.
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