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L-CYSTINE DIHYDROCHLORIDE

Bio Excipient Grade Tris Hydrochloride THCL-3250은 부형제로 사용하기에 적합합니다. ICH-Q7 Good Manufacturing Practice Guide에 따라 제조됩니다. 이 등급의 Tris Hydrochloride는 활성 제약 성분, 의약품 또는 가정 용품으로 사용하기에 적합하지 않습니다.

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Ingredients that foster sustainable development by aiding in climate change mitigation or adaptation, promoting water conservation, supporting a circular economy, preventing pollution, safeguarding biodiversity, or advancing a more ethical and socially just economy.

SODIUM DECANOATE

Sodium Decanoate, or sodium caprate, is the sodium salt of caproic acid, a 10-carbon saturated fatty acid. It has amphiphilic character and can form micelles and liquid crystalline phases in aqueous solution. Sodium decanoate’s properties may help elucidate the transport of biologically active molecules and as a final component of a finished drug product, it may serve to enhance the bioavailability of the API. BioSpectra’s Bio Excipient Grade of Sodium Decanoate is supported by a Type IV drug master file submitted with the FDA.

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GUANIDINE THIOCYANATE, GMP EXCIPIENT GRADE GTHI-3220

Guanidine Thiocyanate is a chaotropic agent. As one of the strongest protein denaturants, it inactivates nucleases more than twice as fast as Guanidine Hydrochloride. Guanidine Thiocyanate is preferred for the purification of RNA because it dissociates the RNA into its nucleic acids and protein forms. Higher molarity solutions of Guanidine Thiocyanate irreversibly inactivate RNase. Guanidine Thiocyanate causes proteins to dissolve readily, thus disintegrating cellular structures.

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TROMETHAMINE (TRIS BASE) USP, EP, JP, LBLE, GMP EXCIPIENT GRADE TRIS-3255

Tromethamine (Tris), is commonly used as a buffer and excipient in biological applications downstream in the manufacture of drug products. Tris is considered a “Good’s” buffer because it has low UV absorptivity, minimal reactivity, stable pH and is soluble in water.

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