ACTIEV CICA CALLUS is Plant-derived exosome isolated and purified from the culture medium of Centella asiatica callus cells. The callus culture is induced using a proprietary process based exclusively on three controlled physical stimuli: UV light, mechanical vibration, and low temperature.This is the world’s first Centella asiatica callus culture produced through a combination of physical stimuli without chemical elicitors. UV stimulation enhances callus cell activity, leading to increased exosome secretion. UV-treated callus cells release exosomes with enhanced skin-relevant benefits, reflecting the adaptive stress response of plant cells under controlled UV exposure. The resulting exosomes support key skin functions, including skin regeneration, hydration, and barrier support. They contribute to the activation of skin repair mechanisms, promote collagen synthesis, and help improve skin moisturization.