Biopharma

Fibronectin (rFN-CH296, NovoNectin) is involved in cell attachment, spreading, differentiation, and proliferation. It can greatly improve the infection efficiency of retroviruses on mammalian cells. VLA-4 and VLA-5 on the cell surface bind to the CS-1 site and the cell-binding domain on NovoNectin, respectively, and the retroviral vector binds to the heparin-binding domain, thus promoting the transfection efficiency of retroviruses and lentiviruses on cells. NovoNectin® can be mixed with anti-Human CD3 mAb for coating to enhance T cell amplification. Recombinant Human NovoNectin is expressed by E. coli, and is produced with raw materials of pharmaceutical applicable level. The host protein residue, nucleic acid residue and common pathogens are strictly controlled, and the production and quality management procedures of the product comply with GMP regulations to ensure the traceability of the production process and all raw materials.

Fibroblast growth factor 9 (FGF-9) belongs to the fibroblast growth factor (FGF) family. Members of the FGF family have a broad range of mitogenic and cell survival activities and are involved in various biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth, and invasion. FGF-9 plays a crucial role in regulating embryonic development, cell proliferation, cell differentiation, and cell migration. Additionally, FGF-9 may be involved in the growth and differentiation of glial cells during development, glial proliferation during brain tissue repair and regeneration after injury, differentiation and survival of neuronal cells, and stimulation of the growth of gliomas. Recombinant Human FGF-9 is expressed by E.coli, and is produced with raw materials of pharmaceutical applicable level. The host protein residue, nucleic acid residue and common pathogens are strictly controlled, and the production and quality management procedures of the product comply with GMP regulations to ensure the traceability of the production process and all raw materials.

Recombinant Human Fibroblast Growth Factor Basic (FGF basic or FGF2/bFGF) is a member of the FGF family. It is a heparin-binding growth factor secreted by endothelial cells, smooth muscle cells, and macrophages. It can promote the proliferation of a series of cells, including mesenchymal cells, neuroectoderm, vascular endothelial cells, and smooth muscle cells. FGF basic serves for angiogenesis regulation, wound healing and tissue repair, embryonic development and differentiation, neuronal protection, etc. Recombinant human FGF basic is expressed by E. coli , and is produced with raw materials of pharmaceutical applicable level. The host protein residue, nucleic acid residue and common pathogens are strictly controlled, and the production and quality management procedures of the product comply with GMP regulations to ensure the traceability of the production process and all raw materials.

Epidermal Growth Factor (EGF) is capable of enhancing the proliferation and differentiation of mesenchymal cells and epithelial cells. In vitro, EGF plays a role of mitogen for fibroblasts, epithelial cells, and endothelial cells, facilitating colony formation in epithelial cell culture. In vivo, EGF promotes epithelial cell and blood vessel formation and inhibits gastric acid secretion. Recombinant Human EGF is produced by E.coli expression system, and is produced with raw materials of pharmaceutical applicable level. The host protein residue, nucleic acid residue and common pathogens are strictly controlled, and the production and quality management procedures of the product comply with GMP regulations to ensure the traceability of the production process and all raw materials.